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One of the downsides of Listerine is its strong alcohol scent. This scent can be uncomfortable for users and may be unpleasant for those with sensitive skin. Additionally, some users may experience a burning or stinging sensation in their mouths when using Listerine. Due to its high alcohol content, individuals sensitive to alcohol should exercise caution when using it. Long-term use can eliminate beneficial oral bacteria and cause adverse effects on oral health. Finally, Listerine is a relatively expensive product, which can be a burden on your budget. For these reasons, it is important to consider these drawbacks before use.