When is the best time to use acne patches for best results?

I put on acne patches whenever breakouts appear, but I still don't really know exactly when is the best time to use them.

It doesn't seem to have much effect when applied to red pimples that have just started to pop up, and

I found that applying it after the white bumps had formed gave a calming effect.

However, if you apply it too late, there are many cases where marks remain, perhaps because it has already been touched by hand.

I am also confused about whether I should apply it after washing my face and before skincare, or after applying all my basic skincare products and as the last step.

For those of you who use acne patches frequently, when do you apply them?

I'm wondering if it's better to apply it before squeezing, after squeezing, or right away when I feel like a breakout is about to occur.

I am also concerned that it is more noticeable when I apply makeup after putting on the patch.

Experts, please let me know in the comments.